Randomized trials with Se as part of multivitamin supplementation in Se-deplete areas were shown to reduce gastric cancer, stroke and overall mortality, but did not reduce the risk for hypertension, CVD or cataracts ( Reference Huang, Caballero and Chang 9 )
Studies show it may be well tolerated in higher doses of 700mg three times a day, as well, with few to no adverse effects when taken as an oral supplement (but we dont recommend taking more than what a supplement manufacturer instructs).31 That's not to say that adverse effects aren't out of the question
They found that participants lost an average of 15.1% of their total body weight over a 68-week period
& Schofield, C
Louis, which hasnt gotten enough regard, shows that high protein intake, and this is shown both in mice and in people, will add to inflammation of the body, and at least in the mice models, promote atherosclerosis. And in fact, the leucine, as you mentioned, Howie, thats the essential amino acid