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Gradual dose escalation over 16-20 weeks greatly reduced the incidence of nausea and vomiting compared to faster titration, while still achieving excellent weight loss outcomes

Statistical analysis Statistical analysis was performed using parametric two-way mixed model ANOVA (one factor is repeated-measures) and Student Newman-Keuls test to compare the difference between groups

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Peptide therapy involves the use of specific short chains of amino acids called peptides that act as signaling molecules in the body, directing cells to perform specific functions

Allergic contact dermatitis: Usually linked to a known allergen and may improve with avoidance