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In experiments involving mouse models exposed to CS, exposure to GHK-Cu was linked to a potential decrease in the production of pro-inflammatory cytokines, including interleukin-1 (IL-1) and tumor necrosis factor- (TNF-), found in bronchoalveolar lavage fluidfluid used to capture cells and soluble factors from the airways and lung tissues

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The article says that once medication has been left unrefrigerated for extended periods or exposed to extreme temperatures, integrity cannot be assumed even if appearance looks normal, and use should stop