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The delivery methods also differ considerably - while injections provide controlled, consistent release of medication through subcutaneous administration, patches rely on unproven transdermal delivery that cannot effectively transport the hormone through the skin barrier

Kattan JD, Srinivasan KD, Zou ZM, Goldfarb J, Sampson HA, Li XM

Of the 114 patients who were eligible for inclusion in the study, 38 patients were excluded according to our study exclusion criteria, and 76 patients participated in the study, including 43 individuals assigned to the control and 33 to the intervention group (Fig