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Histological evaluation of eWAT sections at 6 h post-G49 injection revealed rapid changes in adipocyte features with increased number of smaller adipocytes together with presence of TUNEL positive cells and elevations in fibroblast growth factor 21 ( Fgf21 ) mRNA levels (Fig

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In a recent study of a large cohort of newly diagnosed Graves patients, about 75% had no ocular involvement at diagnosis, only 6% had moderate-to-severe GO, and 0.3% showed sight-threatening GO due to dysthyroid optic neuropathy (DON) (17) (Figure 1)