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Interacting roles of gut microbiota and T cells in the development of autoimmune hepatitis

These effects are thought to occur through GLP-1s influence on both peripheral (vagal) and central pathways, including the hindbrain, hypothalamus, and brain regions involved in motivation and reward, which help regulate appetite and metabolism [8, 14, 18]

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One subject with poor blood sugar control (fasting plasma glucose values 500 mg/dL) at baseline was excluded as the primary investigator considered the risk of hyperglycemic hyperosmolar nonketotic coma