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Retatrutide produces approximately 30-50% more frequent GI side effects than tirzepatide at comparable efficacy doses

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The index date, defined as the date of treatment switch, was required to be at least 90 days before data extraction

Studies show that consistent weekly timingcombined with stable meal patternsmay enhance both weight loss outcomes and tolerability

[DOI] [PubMed] [Google Scholar] 25.Dallon B.W., Parker B.A., Hodson A.E., Tippetts T.S., Harrison M.E., Appiah M.M.A., Witt J.E., Gibbs J.L., Gray H.M., Sant T.M., et al