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Despite accurate diagnosis and early treatment approaches, the outcome for OC patients remains poor since chemotherapys efficiency is restricted by resistance and off-site effects (Figure 7

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It is also important to ascertain how long the depigmenting effect thus achieved would last and what the long-term effects would be on skin color by repetitive treatments lasting several weeks

J Eur Acad Dermatol Venereol 13(3):205209 Malaguarnera M, Gargante MP, Russo C, Antic T, Vacante M, Malaguarnera M, Avitabile T, Volti GL, Galvano F (2010) l-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitisa randomized and controlled clinical trial