GLP-1 medications are glucagon-like peptide-1 (GLP-1) receptor agonists approved for treating Type 2 diabetes and, more recently, for chronic weight management
However, during increased electron flux, superoxide production may reach a critical threshold, which may allow trafficking of superoxide anions through the mitochondrial transition pore into the cytosol, in which further damage and/or the activation of additional ROS sources may occur
However, some pathologists use focal for both focal and multifocal, referring to the nature of the lesion rather than its actual distribution and using grading to reflect the extent of the multifocality
In Ireland, both medications are usually available only with a private prescription and are not currently covered under the Drug Payment Scheme (DPS) when prescribed for weight management
It is similar to a hormone found in the body