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McNaughton SA, Marks GC

2.1 Eligibility criteria for this review This review includes umbrella meta-analyses evaluating the efficacy of nutritional supplementssuch as n-3 polyunsaturated fatty acids, alpha-lipoic acid, polyphenols, minerals, melatonin, vitamins, inositol, probiotics, and L-carnitinecompared to placebo or alternative treatments in women diagnosed with PCOS using the Rotterdam criteria (21)

Interestingly, mediation analysis showed that TMAOs adverse effect on kidney function strengthened at more severe stages of cardiometabolic disease, implying TMAO synergy with existing pathology (thereby providing 2-hit model)

Uneven pigmentation indicates inconsistent UV exposure to different body areas, not peptide failure

Maintenance Phase: Once adequate B12 levels are achieved, the frequency of injections can be reduced