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Side pathways of glycolysis: the pentose phosphate pathway (PPP), hexosamine biosynthesis pathway (HBP), and polyol pathway In ECs, a portion of glucose enters alternative metabolic routes beyond classical glycolysis

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doi: 10.3390/ijms22020723 14 Martinez-ReyesIChandelNS

References Roberts CK, Hevener AL, Barnard RJ: Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training

Compounds 47 and 48 (Figure 6), with IC 50 values of 0.83 and 0.43 M, respectively, which possess aryl-substituted piperazines with acetamide linkers, showed the best activity as DPP-4 inhibitors