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Summary of recommendations Most scientifically supported for weight loss: Tirzepatide Most accessible: Semaglutide Best non-GLP-1 peptide for moderate weight loss: Tesamorelin In this Review Why you should trust us Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles

Rather than trying to hit your entire protein target in one or two meals, distribute it evenly across the day

Tirzepatide is also a once-weekly injectable, but it works on both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

he is paid a medical advisor for digital healthcare companies in the dementia space (Five Lives SAS, Cognetivity Ltd, Cognes Ltd)

Bottom line Stopping a GLP-1 doesn't automatically mean you'll regain all the weight you've lost or lose every health benefit you've gained