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Mice were not physically restrained and were free to move around their cage, with blood samples taken via the tail vein

Here we report the engineering and preclinical development of a bimodal molecule that integrates NMDA receptor antagonism with glucagon-like peptide-1 (GLP-1) receptor agonism to effectively reverse obesity, hyperglycaemia and dyslipidaemia in rodent models of metabolic disease

Willpower is not the variable

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