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Importantly, investigations suggest that Sermorelin signaling may preserve physiological pulsatility rather than inducing continuous activation, a feature often emphasized in theoretical discussions of endocrine coherence

(2) Raun K, Hansen BS, Johansen NL, Thgersen H, Madsen K, Ankersen M, Andersen PH

Conclusions Nutraceuticals represent promising strategies for preventing, delaying, and addressing premature aging of the skin, especially as women advance in years (particularly after 30 years of age, when estrogen levels begin to decline and remarkably after menopause when estrogen production ceases from the ovaries)