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Biochimica et Biophysica Acta (BBA)
While antioxidants can diminish anxiety-like behavior in rodents [28, 31, 32], the expression of two enzymes associated with the antioxidant glutathione (GSH) system (glyoxalase 1 and GSH reductase 1) in emotion-related brain regions modulates anxiety-like behavior [26]
At the cellular level, measurement of length ( L ) and width ( W ) of isolated cardiomyocytes demonstrated that myocytes were elongated (increased L : W ratio) in the iron group and had an L : W ratio close to normal in the amlodipine-treated group (Figure 3C)
For patients with severe depression, active suicide risk, psychosis, mania, dangerous impulsivity or potential harm to others, medication may be necessary for immediate protection and stabilization