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Findings include reduced infarct size, possible protection against glutamate-induced cell damage, and induction of neuroprotective mediators such as IGF-1 in brain regions including the hippocampus and cerebellum

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Alterations in growth plate development in CartIR / mice / To determine the importance of insulin signaling on growth plate development in vivo , we generated mice deficient in IR in chondrocytes as described in the section on Materials and methods

doi:10.1097/01.prs.0000034327.02735.4e Souza FM, Collett-Solberg PF