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Although glucagon-like peptide-1 (GLP-1) activation is reported to ameliorate oxidative stress by increasing antioxidant levels, the administration of TIR with DXN did not significantly mitigate the effects of DXN on induced cognitive impairment and oxidative stress

These visual and cognitive symptoms are not just "in your head"they are deeply rooted in physiological changes, including neuroinflammation, microvascular damage, and severe oxidative stress

Das P, Eng C, Rodriguez-Bigas MA, Chang GJ, Skibber JM, You YN, Maru DM, Munsell MF, Clemons MV, Kopetz SE , Garrett CR, Shureiqi I, Delclos ME, Krishnan S, Crane CH

doi: 10.1038/s41556-018-0176-2 29 JinSMYouleRJ

As far as I know, the whole time I was using this I didn't experience any major break out, if there is it would just be really small, not quite alarming unlike before