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Medvi is a U.S.-based telehealth healthcare platform designed to deliver medically supervised weight loss programs directly to patients through a secure online interface

They used DPP4-targeted immune therapy by vaccines in a C57BL/6J mouse model and were able to show comparable effects like in treatments with gliptins regarding GLP-1 plasma levels and post-prandial glucose excursion and insulin sensitivity in HFD-fed mice

However, there are some limitations to this study, including a small sample size, a cross-sectional design that limits causal analysis, and data missingness, which may affect the generalizability of the results

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