In addition, studies have shown that TMAO not only causes primary peritoneal mesothelial cell necrosis, but also increases the synthesis of pro-inflammatory cytokines such as CCL2-, TNF-, IL-6, and IL-1 (Zhang et al., 2022)
Exposure to certain chemicals found in personal care products and plastic can interfere with hormone regulation, causing hormonal imbalances that can contribute to PCOS symptoms
These results, published in the New England Journal of Medicine in 2024, exemplify the expanding therapeutic horizons of this drug class
In the process of physiological ageing, both systemic and tissue-specific systems show functional downfalls, which, when projected to the brain, translate into weakening defence and metabolic strain resulting from age-dependent declines of the cardio-vascular system and overall decreases in metabolism
A stool that is particularly dark/black or tarry can be a sign of bleeding further up in the gastrointestinal tract