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Never freeze reconstituted peptides as ice crystal formation denatures the delicate peptide structure, causing 30-50%+ potency loss

Otherwise, a fixed effect model based on the inverse-variance method was applied for trials with no heterogeneity

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PlexusDx sources exclusively from licensed 503A compounding pharmacies, which operate under state board of pharmacy oversight and cannot distribute products like wholesale distributors

Statements Acknowledgments This work was supported by grants from Federico II University of Naples (Italy)