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In contrast, in in vivo assay, xCT-KO pancreatic ductal adenocarcinoma (PDAC) cells injected subcutaneously managed to form a tumor, although with a short delay
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This approach reduces fresh acid consumption, minimizes acidic effluent volume, and decreases washing water requirements by ~75%, thereby limiting acid-containing waste streams
All research personnel were blinded except for one research assistant who created the challenge material, and this person was not involved in data collection
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