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The diagnosis of HT is determined by biochemical (positive circulating thyroid autoantibodies) and imaging tests (hypoechogenic inhomogeneous thyroid structure in ultrasonography) with characteristic clinical features

NO is a gaseous free radical synthesized by NO synthases (NOSs) starting from L-arginine, NADPH and oxygen

Hydroxocobalamin has a higher affinity to the TC II transport protein than cyanocobalamin, or adenosylcobalamin

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This also pinpointed when glutathione is specifically required: during the early steps of metastatic colonization, when cancer cells adapt rapidly to the stressful environment of a new tissue