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b , The pose of TT-OAD2 and interactions with residues within TM1, TM2, TM3, ECL1 and ECL2 are supported by well-resolved density in the cryo-EM map

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Its epidemiology shows marked geographic variation: incidence is highest in North America and Western Europe (920 cases per 100,000 person-years) but is rising rapidly in regions historically considered low risk, including parts of Asia and South America ( Pharmacologic management of UC aims to control inflammation and induce and maintain remission