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Every FDA-approved GLP-1 receptor agonist and GIP/GLP-1 dual agonist carries the class boxed warning for thyroid C-cell tumor risk observed in rodent studies, and all are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Mariscal M., Testai F.D
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Those warnings include thyroid tumor risk and MEN2 contraindications
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