PlexusDx supports precision-wellness conversations by offering baseline genetic and biomarker assessment tools that empower you and your provider to make more informed decisions about peptide dosing, monitoring protocols, and expected response timelines
Prz Gastroenterol (2019) 14(1):2638
Gastrointestinal discomfort may occur in some individuals
Neuropathological investigations in the substantia nigra pars compacta of Parkinsons disease patients demonstrate that deficient PGC-1 expression compromises mitochondrial biogenesis and disrupts the coordinated transcriptional activation of antioxidant stress-responsive gene networks, thereby precipitating dopaminergic neuronal degeneration (Piccinin et al., 2021)
Nutritional factors that may be useful to consider in pain management - evidence indicates substantial relief of neuropathic pain by thiamine, pyridoxine and cyanocobalamin separately, and in combination there was a synergistic benefit, low B12 exacerbates elevated TNF- which is an inflammatory response marker