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It diminishes cytokinin-mediated responses, provides gastric cytoprotection, and reduces vascular permeability

MMPs secreted by trophoblasts and cancer cells can shape the ECM, triggering its remodeling and facilitating invasion and the recruitment of immune cells

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These myeloid immunosuppressive cells disrupt major mechanisms of immunosurveillance, including antigen presentation by dendritic cells, T-cell activation, and/or the cytotoxicity of NK cells