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The 2-year STEP 5 study discussed here aimed to assess the sustained impact of weekly subcutaneous semaglutide 2.4 mg, in conjunction with behavioral interventions, on body weight and cardiometabolic risks among non-diabetic adults grappling with obesity (BMI 30 kg m2) or overweight (BMI 27 kg m2 with at least one related comorbidity)

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While flexible linkers could be successfully used for a fusion enzyme comprising CrtZ and CrtW 22 , this study identified a larger linker (20 aa vs