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Cytokine Production: GLP-1R activation directly inhibits the production of pro-inflammatory cytokines (TNF-, IL-1, IL-6) and increases anti-inflammatory mediators like adiponectin

[PMC free article: PMC3004035] [PubMed: 21173910] (Three women, ages 31, 37 and 53 years, taking Hydroxycut [n=1] or Herbalife [n=2] weight loss formulas developed jaundice 3, 4 and 12 months after starting product [bilirubin 15.3, 29.9, and 18.2 mg/dL, ALT 1227, 2068 and 983 U/L, Alk P 268, 185 and 292 U/L], resolving within 2-3 months of stopping)

For most people, GLP-1 side effects are not dangerous

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Dietary protein intake plays a critical role in muscle preservation