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However, genetic predisposition is not destinylifestyle, nutrition, and biomarker status also matter significantly

Acknowledgements Studies performed in the authors laboratories were supported by Grants-in-Aid from the Japan Agency for Medical Research and Development (JP21gm1010002, JP22bm0804005, and JP22ek0109488), the Japan Society for the Promotion of Science (JP20H03561, JP22K17343, and JP22K15394), the Ministry of Health, Labor, and Welfare of Japan (20FC1036), the National Center of Neurology and Psychiatry (25), and the Hori Science and Arts Foundation

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