Additional ultrastructural changes may rarely include dilated granular endoplasmic reticulum, paracrystalline mitochondrial inclusions, and dilation of bile canaliculi, which is a result of impaired excretion of conjugated bilirubin and other organic anions from hepatocytes into the bile canaliculi
The resulting GSH or homoglutathione (-L-glutamyl-L-cysteinyl--alanine) conjugates were usually much less toxic and more water-soluble than the original xenobiotics (Brown and Neighbors, 1) (Bartling et al., 2002
Tranexamic acid has also found to inhibit tyrosinase activity to reduce hyperpigmentation
Zhukovsky MA, Filograna A, Luini A, Corda D, Valente C
AMERICAS GLUTATHIONE MARKET SIZE, BY INJECTABLE, 2018-2032 (USD MILLION) TABLE 216