A: You can, but it's not recommended
doi: 10.1016/j.ymthe.2022.09.002 32 ZhangJRuizMBerghPOHenricssonMStojanoviNDevkotaRet al
J Neurosci Res 84:578586 Lipton AJ, Johnson MA, Macdonald T, Lieberman MW, Gozal D, Gaston B (2001) S-nitrosothiols signal the ventilatory response to hypoxia

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Synaptic memories upside down: bidirectional plasticity at cerebellar parallel fiber-Purkinje cell synapses