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Existen dos estados de glutatin: El tiol reducido (GSH), la forma ms predominante (98% del contenido total del glutatin) El oxidado por disulfuro (GSSG) La produccin de GSH se produce a travs de tres vas principales: Sntesis de novo mediante un proceso de 2 pasos catalizado por la glutamato cistena ligasa (GCL) y la glutatin sintetasa (GS), que est controlada principalmente por los niveles celulares de cistena