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For cohort studies, the age range associated with the RR estimate was calculated as a mean age at baseline plus the mean/median years of follow-up (if only the maximum years of follow-up were reported, we would halve this value and add it to the mean age at baseline)

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On a global scale, the WHO suggested stopping the promotion of electronic cigarettes to non-smokers and young people, and restricting the possibilities of advertising and indoor use.100 Likewise, the American College of Preventive Medicines Prevention Practice Committee recently issued a consensus-based statement recommending that electronic nicotine delivery systems should be screened in the general population, with special emphasis on electronic nicotine delivery systems initiation prevention among youth, but also in smokers intending to quit.101 In 2016, the US Food and Drug Administration (FDA) firmly regulated cigarettes and smokeless tobacco, including electronic cigarettes, prohibiting their sale to teens and even distribution of free samples

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neck pain), which were usually reported as either mild or moderate and resolved shortly after treatment