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Other potential risks include pancreatitis, gallbladder disease, diabetic retinopathy complications (with semaglutide), and acute kidney injury if dehydration occurs

Duration of treatment comparison Trial duration differences complicate raw comparisons

52 Consequently, a novel regulation mode of lactylation using lactate as a direct donor without necessitating the formation of lactyl-CoA is proposed, expanding the substrate range of lactylation

The compound remains at the investigational stage and its human safety profile has not been validated

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