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Existen varios grupos de personas en los que la suplementacin con L-carnitina debe evitarse o hacerse bajo estricta supervisin mdica: Personas con enfermedad cardiovascular establecida , debido al posible aumento del metabolito TMAO, que se asocia a mayor riesgo de eventos cardiovasculares

The mRNA level of asparagine synthetase ( ASNS ), which plays roles in protein synthesis, was significantly decreased in the L-carnitine group in the fasting state, both the liver and muscle (Fig