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10.1002/jcb.25533 4 Al-HendyA.SalamaS

Isotretinoin blood concn-time curves following a single- or multiple-dose regimen are well described by a linear model with biphasic disposition characteristics

Barrientos, S., Brem, H., Stojadinovic, O., & Tomic-Canic, M

The 0.01 mg/kg dose that showed consistent effects in rats translates to approximately 0.0016 to 0.004 mg/kg in humans, which works out to roughly 0.112 to 0.28 mg for a 154-pound person