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Tirzepatide adds GIP (glucose-dependent insulinotropic polypeptide) receptor agonism

J Pers Med [Internet]

Researchers interested in GLP-1-based therapies may be familiar with liraglutide, classed along with semaglutide as a long-acting GLP-1RA hypoglycemic agent and approved for the treatment of type 2 diabetes and chronic weight management [17]

In an aspect of second embodiment, present invention involves the preparation of fusion tag construct of Formula (II) comprising fusion of amino terminal of a synthetic nucleotide of semapeptide with carboxyl terminal of fusion tag construct