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As an example, in experimental conditions with animal models (GLP-1R-null), TZP reduced appetite and food intake, liver glycogenolysis and gluconeogenesis, improved insulin sensibility (assessed by euglycemic clamp) and glucose disposal in white and brown adipose tissue, skeletal muscle, with body weight-dependent and independent effects (73)

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doi: 10.1016/j.bbrc.2017.06.031 25 NybergJJacobssonCAndersonMFErikssonPS

hence, it is more preferable than cyanocobalamin for the treatment of vitamin B12 deficiency

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