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Level of evidence This recommendation is based on a meta-analysis that conducted a head-to-head comparison between combination therapies based on incretins (short- and long-acting GLP-1 RAs, glucose-dependent insulinotropic polypeptide [GIP]/GLP-1 RAs such as tirzepatide) and those based on basal insulin in people with T2DM [506]

These changes may contribute to metabolic improvements independently of weight loss

It is a highly bioavailable form of L-Carnitine that supports energy production and cognitive function