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A review: Role of ultraviolet radiation in age-related macular degeneration

For example, studies of healthy females found that the low level of serum folate in 677TT genotype is associated with an increase in homocysteine concentration and DNA hypomethylation 91,92 , which reveals the association between MTHFR C677T polymorphisms and nutrient status

The compliance question is not the state, it is the source

This study was small and has not been replicated

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