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The genetic test examines variants such as GLP1R rs6923761, GIPR rs1800437, FTO rs9939609, and MC4R rs17782313all linked to appetite regulation and metabolic function

One participant was withdrawn owing to a non-serious adverse event of drug hypersensitivity after IcoSema administration, two participants withdrew consent during the study, and one participant was withdrawn upon decision by the sponsor

too high signals overresponse and is a contraindication to continuing