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Patients from 10 to 50 years of age and both sexes were included if they complained of stable acral vitiligo and have not received any form of vitiligo treatment during the last 3 months before recruitment

DMPs associated with MAPK and mTOR signaling pathways were extracted for Gene set enrichment analysis (GSEA) using the clusterProfiler package, based on log-fold changes aggregated at the gene level from DMP results

Minimal differences were observed in the nucleotide metabolism and the TCA cycle between aged Mda5 -/- and WT HSCs (Supplementary Fig

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