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COPD is a heterogeneous condition, with between-individual variation in the nature and severity of airway inflammation [42] and the inflammatory cell profile also varies in large and small airways and with severity of COPD, hence careful appraisal is needed [43]

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As stated above, optometrists should begin asking patients as young as age 9 about their tobacco use

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American Original Edition Original Red Nicotine content: 0.8 Tar content: 12.0 It was released in 1967 with the dissemination of filter cigarettes, and was discontinued due to low sales volume in 2006