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Based on the available data, Orderly Meds falls somewhere in the middle of the spectrum on this metric

Although no data from head-to-head trials comparing retatrutide to other currently approved obesity treatments exist, data from the phase 2 studies with retatrutide suggest that at higher doses, retatrutide could lead to greater WL compared to the most efficacious approved treatments for obesity and T2D such as tirzepatide 15 mg and semaglutide 2.4 mg (Fig

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Although the effect of GLP-1 was not apparent in the above analyses, a transient effect of GLP-1 was detected when data were analyzed in shorter time bins (Fig