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This was a randomized, double-blinded, placebo controlled crossover study involving 49 volunteers who consumed beer to obtain a breath alcohol content (BrAC) of 0.1 g/210L

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On ice, cells were scraped and collected in extraction buffer containing methanol:acetonitrile:H 2 O (4:4:2), 15 M glutaric acid and 0.5% formic acid

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