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The risk of amputation was highest in patients with a baseline history of diabetic foot, peripheral artery disease (including previous amputation) or diabetes

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North American and AsiaPacific production contributes approximately 2000 t year 1 (FAO., 2022)

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Necroptosis of erythrocytes relies on the RIPK1 (receptor-interacting serine/threonine-protein kinase 1)/RIPK3 (receptor-interacting serine/threonine-protein kinase 3)/MLKL (mixed lineage kinase domain-like pseudokinase), similarly to nucleated cells