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Quick Takeaways Strong healing effects observed in animal studies

Some peptides influence inflammation pathways in laboratory and animal studies, but high-quality human evidence specific to knee inflammation is limited

[DOI] [PubMed] [Google Scholar] 13.Mellman I, Coukos G, Dranoff G

Your body produces this compound naturally in the liver

There is some thought that since Pycnogenol can improve endothelial function and reduce catecholamine excess, it might actually mitigate some physical side effects of stimulants (like if a stimulant raises heart rate, Pycnogenol might blunt that increase a bit by improving vascular function)