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This level of precision is overkill for standard dosing but invaluable for microdosing protocols where researchers work with doses of 0.25 mg to 1 mg

This makes injections a safe and sustainable way to maintain optimal levels over time

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The molecular basis of this persistence involves retention of 44.6% of altered DNA methylation patterns (367 loci) (108) and persistence of 532 histone modification sites that continue to influence germline gene expression (109)

Systemic and topical administration work through different pathways, potentially complementing each other