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Andrographolide alleviates Parkinsonism in MPTP-PD mice via targeting mitochondrial fission mediated by dynamin-related protein 1

Long-term safety for broad wellness use is not well established

A pharmacokinetics study published in Frontiers in Pharmacology found an average intravenous elimination half-life (t1/2) of 15.2 minutes in rats, with the intramuscular peak plasma concentration reached at 3 minutes post-injection

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