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Meeting these strict criteria ensures that the medication is prescribed solely for those who truly need it for medical health improvements
However, clinical data in humans remains limited
A limited number of studies extended their inclusion to non-diabetic obese populations (e.g., the adolescent obesity trial by Kelly 2020 and the obesity intervention trial by Tronieri 2019)
The pathological characteristics of the vehicle group were consistent with the clinical definitions of IF/TA and i-IFTA based on the Banff classification
Retatrutide is investigational and Phase 3 trials are ongoing as of 2026
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